Merkel Cell Carcinoma in a Cat
نویسندگان
چکیده
منابع مشابه
NOTE Pathology Merkel Cell Carcinoma in a Cat
A 17-year-old spayed female Japanese domestic cat presented with a solitary cutaneous mass in the right thoracic area. Histopathologically, the mass consisted mainly of round tumor cells that had infiltrated throughout the dermis and deep subcutaneous tissue. The proliferating pattern of tumor cells was solid but also trabecular or cord-like in some areas, and lined with small cells resembling ...
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conclusions the findings of this study are consistent with the hypothesis that local, systemic, or tumor-induced immunosuppression may allow the mcpyv to initiate skin aggressive cancer. it is necessary to maintain regular check over patients taking immunosuppressive medications for mcpyv infection. since there is not any information about detection and molecular biology analysis of mcpyv among...
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The RNA viruses hepatitis C virus and human T-cell lymphotropic virus type I (or human T-cell leukaemia virus type 1), and the DNA viruses hepatitis B virus, high-risk human papillomaviruses, human herpes virus-8 (Kaposi’s sarcoma-associated herpes virus) and Epstein Barr virus are acknowledged as carcinogenic to humans. Human polyomaviruses have oncogenic potentials in cell cultures and animal...
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We investigated whether Merkel cell carcinoma (MCC) patients in France carry Merkel cell polyomavirus (MCPyV) and then identified strain variations. All frozen MCC specimens and 45% of formalin-fixed and paraffin-embedded specimens, but none of the non-MCC neuroendocrine carcinomas specimens, had MCPyV. Strains from France and the United States were similar.
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Merkel cell polyomavirus (MCPyV) DNA was detected in 88% of Merkel cell carcinomas in contrast to 16% of other skin tumors. MCPyV was also found in anogenital and oral samples (31%) and eyebrow hairs (50%) of HIV-positive men and in forehead swabs (62%) of healthy controls. MCPyV thus appears to be widespread.
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 2009
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.71.1093